Community and Mission Hospital of Huntington Park will start suspending operations at its Mission campus on Friday. About 100 workers will be laid off or transferred.

Karykeion Inc., which bought the two-campus hospital from Tenet Healthcare Corp. at the end of 2005, said severe financial losses could have led to the closure of the 157-bed institution unless services were cut. The hospital is largely dependent on Medi-Cal and similar government programs, and reported a $3.4 million loss in 2006 because the programs don’t pay enough to cover the cost of operations.

The urgent care center at Mission was closed last year. Mission, which houses the hospital’s pediatric and obstetrics wards, will stop admitting patients. Community handles adult acute cases and operates a 24-hour standby emergency room with 30,000 visits a year. It can absorb some pediatric cases but expectant mothers will probably have to go to another area hospital.

Chief Executive Dennis Coleman said he will attempt to fill as many vacancies as possible at Community with former Mission employees. About 400 workers at both facilities were notified of the closure two weeks ago. The workers are represented by SEIU United Healthcare Workers West.

“I don’t know what this community is going to do,” said Dr. Amal Zuky, who has run a family practice near the hospital for 26 years. “This area is 99 percent Medi-Cal and many people don’t have their own transportation.”