NET WORTH: $1.85 billion, up 8.8 percent

LAST YEAR: $1.7 billion

AGE: 66

RESIDENCE: Los Angeles

SOURCE OF WEALTH: Surgical devices, patents, investments

THE MONEY: Took $1.35 billion windfall from 2005 patent infringement settlement with Medtronic and invested it in Karlin Asset Management family office and ongoing philanthropic efforts. Diversified holdings include real estate and global equities.

BUZZ: USC started construction on Michelson Center for Convergent Bioscience in October, will be largest building on campus. Retired orthopedic surgeon and his wife, Alya, gave $50 million last year to fund center. Animals a philanthropic interest; funding $75 million Michelson Prize and Grants in Reproductive Biology to reduce number of pets euthanized annually. Has donated more than $100 million for medical research in genetic disorders, neurodegenerative diseases, spinal cord regeneration, infertility and other issues. Born in Philadelphia, raised by mother and grandmother, who suffered from crippling spinal deformity. Inspired to become orthopedic surgeon. Holds more than 250 patents on instruments, methods and devices related to orthopedic surgery.